Disclosure of Genome Sequencing Results: Are Pediatricians Ready?

In this issue of Pediatrics, McCullough et al use the tools of ethical analysis and argument to address the issues surrounding the disclosure of genome sequencing results, specifically whole exome sequencing (WES) and whole genome sequencing (WGS). From this analysis, they develop a framework for pediatricians to use in their practice to address the unique issues surrounding the disclosure of WES/WGS results. This review is particularly helpful because it addresses issues regarding genetic testing that were not readily apparent when the 1995 American Academy of Pediatrics’ Committee on Bioethics report was written. In this world of rapidly changing genetic testing, revisiting our previously wellthought-out guidelines is an important step.